Age 30–59 with high lifetime risk, or a major risk enhancer (e.g. premature family history, South Asian ancestry) or elevated Lp(a)? Yes
risk-low-enhancersFewer than 5 people have reached this rule so farDiscuss a statin anyway — the calculator under-weights these
No clinician has signed off this rule yet. It reflects our reading of the guidelines cited below, which has not been independently checked.
Word for word, as generated for the example person below. Figures in the text are theirs.
Your calculated risk is low, but talk to your doctor about a statin anyway — the calculator under-weights the factors you have.
Your estimated 10-year PREVENT-ASCVD risk is 1.2%, below the 3% threshold — but the equations are blind to what you have: south asian ancestry. A low score does not rule out benefit from a statin when the thing raising your risk is something the calculator never sees.
2026 ACC/AHA/Multisociety Guideline on the Management of Dyslipidemia · Class 2b
“Low calculated risk, South Asian ancestry” — an illustrative profile, not a real user.
Asked after: 10-year risk under 3%
Then asks: Coronary artery calcium (CAC) score? (further testing beyond basic labs)
Cited by the recommendations above.
For practising clinicians. Endorse it, propose a change, or dispute it. We verify every reviewer before a review is shown, and a review stays attached to the version of the rule you saw — if the rule changes, the page says so. You'll be asked to declare any relevant interests; they're shown with your review.
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Runs in lib/engine/lipidPathway.ts as risk-low-enhancers.