Your situation (severe hypercholesterolemia short-circuits the risk score) 10-yr PREVENT-ASCVD 5–<10% (intermediate)
risk-5-to-10No one has reached this rule yetStatin should be started; LDL-C <100, non-HDL-C <130 (30–49% reduction)
No clinician has signed off this rule yet. It reflects our reading of the guidelines cited below, which has not been independently checked.
Word for word, as generated for the example person below. Figures in the text are theirs.
Statin therapy should be started, aiming for LDL-C below 100 mg/dL (and non-HDL-C below 130) — which usually means cutting your LDL by 30-49%.
Your estimated 10-year PREVENT-ASCVD risk is 5.6%, in the guideline's "intermediate" band of 5% to just under 10%. Worth being precise about the goal: the LDL target of 70 belongs to the high-risk group at 10% and above, not to this band. Treatment is clearly recommended for you; the target is 100.
2026 ACC/AHA/Multisociety Guideline on the Management of Dyslipidemia · Class I
“Intermediate risk” — an illustrative profile, not a real user.
Asked after: No known cardiovascular disease
Then asks: Coronary artery calcium (CAC) score? (further testing beyond basic labs)
Cited by the recommendations above.
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Runs in lib/engine/lipidPathway.ts as risk-5-to-10.