Heart Health

Aspirin with known heart disease

Known cardiovascular disease? Yes

Recommendationaspirin-secondaryNo one has reached this rule yet

Low-dose aspirin is standard unless a doctor has stopped it

Clinical review

All reviewers

No clinician has signed off this rule yet. It reflects our reading of the guidelines cited below, which has not been independently checked.

What someone who reaches this rule is told

Word for word, as generated for the example person below. Figures in the text are theirs.

  • Strongly recommended

    Low-dose aspirin (usually 81 mg daily) is standard for you unless your doctor has specifically stopped it.

    Proven in trialsTrials counted real events, like heart attacks, strokes, or deaths, and this changed them.

    ACC/AHAClass 1Level AESCClass ILevel A
    Why, and the source

    Once you've had a heart attack, stroke, or stent, aspirin's benefit clearly outweighs its bleeding risk. This is one of the few places aspirin is still unambiguous. Don't stop it on your own — that carries real risk.

    Where the guidelines stand

    ACC/AHA (US)

    • RecommendsClass 1Level A

      The chronic coronary disease guideline grades low-dose aspirin (75 to 100 mg) for people with no indication for an oral anticoagulant. For symptomatic peripheral artery disease a single antiplatelet drug is also Class 1, Level A.

      2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Pati… · Recommendation behind this rule · class and level read from the guideline tables on 2026-09-30

    ESC (Europe)

    • RecommendsClass ILevel A

      Aspirin 75 to 100 mg daily is recommended lifelong after bypass surgery (I, A), and clopidogrel is an equal alternative after a heart attack or stent (I, A). Without a prior heart attack or revascularization but with significant obstructive coronary disease it is I, B.

      2024 ESC chronic coronary syndromes guidelines · Recommendation tables · class and level read from the guideline tables on 2026-09-30

    2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease · Class 1 · Level A

An example person who reaches it

“Known heart disease” — an illustrative profile, not a real user.

63-year-old manBP 128/78LDL 92prior heart attack or stenton a statin10-yr PREVENT-ASCVD 4.1%

Their path through prevention essentials

  1. Known cardiovascular disease?Yes ← this rule
  2. On a statin, or is one indicated?Yes
  3. Has Lp(a) ever been measured?No

Sources

Cited by the recommendations above.

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Runs in lib/engine/preventionEssentials.ts as aspirin-secondary.