Heart Health

Lp(a) never measured

Has Lp(a) ever been measured? No

Testlpa-not-measuredNo one has reached this rule yet

Measure it once — it is inherited and nothing else on the page reveals it

Clinical review

All reviewers

No clinician has signed off this rule yet. It reflects our reading of the guidelines cited below, which has not been independently checked.

What someone who reaches this rule is told

Word for word, as generated for the example person below. Figures in the text are theirs.

  • A test worth considering

    Ask for a lipoprotein(a) test — once, ever. It's a single blood draw and most people have never had it.

    Expert guidelinesOfficial guidelines recommend it, based on trials plus expert judgment.

    ACC/AHAClass 1Level B-NRESC/EASClass IIaLevel C
    Why, and the source

    About 1 in 5 people carry an elevated Lp(a), it's almost entirely inherited, it doesn't change much over your lifetime, and nothing else on this page would reveal it — not your cholesterol panel, not a calcium scan. Knowing it can change how aggressively your LDL should be treated, and it tells your siblings and children something about their own risk.

    Where the guidelines stand

    ACC/AHA (US)

    ESC (Europe)

    • RecommendsClass IIaLevel C

      Lp(a) measurement should be considered at least once in each adult's lifetime. The 2025 update adds Lp(a) above 50 mg/dL as a risk-enhancing factor (IIa, B).

      2019 ESC/EAS dyslipidaemia guidelines · Recommendation tables · class and level read from the guideline tables on 2026-09-30

    2026 ACC/AHA/Multisociety Guideline on the Management of Dyslipidemia · Class 1 · Level B-NR

An example person who reaches it

“Low risk, nothing flagged” — an illustrative profile, not a real user.

42-year-old womanBP 118/74LDL 10010-yr PREVENT-ASCVD 0.6%

Their path through prevention essentials

  1. Known cardiovascular disease?No
  2. Has Lp(a) ever been measured?No ← this rule

Sources

Cited by the recommendations above.

What we are least sure of here

  • Q19Should test verdicts be framed as 'what decision would this change?' rather than 'worth doing'?

Review this rule

For practising clinicians. Endorse it, propose a change, or dispute it. We verify every reviewer before a review is shown, and a review stays attached to the version of the rule you saw — if the rule changes, the page says so. You'll be asked to declare any relevant interests; they're shown with your review.

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Runs in lib/engine/preventionEssentials.ts as lpa-not-measured.